hair loss gene | Hair Loss Radio Show: The Bald Truth

APCDD1- Researchers Identify Hair Loss Gene

Scientists from from Colombia, Rockefeller and Stanford Universities, believe they have discovered a gene that significantly impacts hair growth as well as hair follicle miniaturization; the phenomenon that is the cornerstone of male and female pattern baldness.

The gene identified is named APCDD1 (adenomatosis polyposis down-regulated 1), and was found in patients suffering with hereditary hypotrichosis simplex, a condition that usually presents itself in childhood. Hereditary hypotrichosis simplex is a rare autosomal dominant form of hair loss characterized by hair miniaturization, a process in which the hair follicle actually shrinks and normal thick terminal hair is gradually replaced with fine, velus hair.
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Hair Loss Genes Discovered, What Does This Mean For Us?

Has science finally found the Holy Grail for the follically challenged? Probably not, but it does appear that we are getting closer.

Two articles published in Nature Genetics may help to better explain the genetic predisposition to male pattern hair loss, and to one day give scientists the ability to grow DHT resistant hair follicles for use in hair restoration.

The first article was published by researchers at McGill University, King’s College London and GlaxoSmithKline Inc. These researchers identified two genetic variants in men that together produce an increased incidence of male pattern hair loss that is seven times greater than those without these variants. Read more ›